Neuropeptides & CNS Signaling
Pre-Clinical Neurotrophic Expression & Central Synaptic Modulation
Reference monographs documenting synthetic heptapeptides and regulatory fragments evaluated for neuroprotective signaling, brain-derived neurotrophic factor (BDNF) transcription, and monoaminergic receptor interactions in neurological assay systems.
Reagents in this Signaling Category
Semax
Heptapeptide ACTH(4-10) Analog (Met-Glu-His-Phe-Pro-Gly-Pro)
Semax is a synthetic regulatory heptapeptide structurally derived from an adrenocorticotropic hormone fragment (ACTH 4-10) stabilized with a C-terminal Pro-Gly-Pro tripeptide. Examined in neuropharmacology laboratories for its modulation of BDNF, trkB receptors, and cerebral monoamines.
Selank
Synthetic Tuftsin Heptapeptide Analogue (Thr-Lys-Pro-Arg-Pro-Gly-Pro)
Selank is a synthetic regulatory heptapeptide derived from the immunomodulatory tetrapeptide tuftsin, extended with a C-terminal Pro-Gly-Pro tripeptide. Examined in neuroimmunology laboratories for its allosteric modulation of GABAA receptors, enkephalinase inhibition, and IL-6 expression.